Dr. Arindam Majumdar

M.B.B.S., M.S. (Gynecologist & Obstetrician)

Reg. No. 64861 (WBMC)
Consultant Gynecologist & Obstetrician
Formerly Senior Resident NRS Medical College & Hospital
Fellowship in IVF World Laparoscopy Hospital, New Delhi.

Recurrent Pregnancy Loss

What causes recurrent pregnancy loss?

A woman's immune system may also play a role in recurrent pregnancy loss. Hormone abnormalities may also impact pregnancy loss, including thyroid disease and diabetes. Abnormalities in a mother's blood clotting may also affect pregnancy loss.

Is recurrent miscarriage considered infertility?

Recurrent Pregnancy Loss. Miscarriage is one of the most devastating experiences that can happen to a woman. Approximately two out of every 10 pregnancies may result in a miscarriage. Therefore, after having one miscarriage, most women go on to have a healthy pregnancy.

How common is recurrent missed miscarriage?

Just 2 percent of pregnant women experience two pregnancy losses in a row, and only about 1 percent have three consecutive pregnancy losses. The risk of recurrence depends on many factors. After one miscarriage, the chance of a second miscarriage is about 14 to 21 percent.

How is recurrent miscarriage treated?

Treatment for recurrent pregnancy loss can involve a range of options including careful monitoring and pre-natal care, surgery, hormone therapy, antibiotics and the use of procedures such as in vitro fertilization. Appropriate treatment has proved to be both safe and effective for most couples.

Can sperm cause a miscarriage?

Recurrent miscarriage can be caused by several factors including abnormal chromosomes in the foetus, female hormonal problems or issues with the woman's womb. Another significant factor in recurrent miscarriage is the quality of the man's sperm DNA.

Are you fertile after having a miscarriage?

You can ovulate and become pregnant as soon as two weeks after a miscarriage. Once you feel emotionally and physically ready for pregnancy after miscarriage, ask your health care provider for guidance. After one miscarriage, there might be no need to wait to conceive.

Are you more fertile after a miscarriage?

Women are more likely to have a successful pregnancy if they conceive sooner after a miscarriage rather than waiting, researchers have found. The University of Aberdeen team said conceptions within six months were less likely to result in another miscarriage or preterm birth.

What causes recurrent miscarriage?

Another possible cause of recurrent miscarriage is a congenital anomaly of the uterus. Examples include a septate uterus, adhesions and scarring of the uterus, an incompetent cervix, fibroids, and polyps.

How long should you wait after miscarriage to try again?

After a miscarriage, how soon can you try to get pregnant again? In the United States, the most common recommendation was to wait three months for the uterus to heal and cycles to get back to normal. The World Health Organization has recommended six months, again to let the body heal.

Why do I have so many miscarriages?

Why Do Miscarriages Happen? The most common cause of pregnancy loss is a problem with the chromosomes that would make it impossible for the fetus to develop normally. Other factors that could contribute to a miscarriage include: abnormal hormone levels in the mother, such as thyroid hormone.

Can low estrogen cause miscarriage?

Lack Of Estrogen Causes Miscarriage: Restoring Normal Estrogen Levels Maintains Pregnancy. ... Researchers studying the role of estrogen in pregnancy have found that low estrogen levels caused miscarriages in more than 50 percent of pregnant baboons, primates whose hormones during pregnancy act much like those of humans.

What tests are done for recurrent miscarriage?

Hormone Tests. Because the risk for recurrent miscarriage increases with age, women ages 35 and older may have a blood test that checks for the level of follicle-stimulating hormone, or FSH.

What is recurrent pregnancy loss?

Recurrent pregnancy loss (RPL), also referred to as recurrent miscarriage or habitual abortion, is historically defined as 3 consecutive pregnancy losses prior to 20 weeks from the last menstrual period.

How do you confirm a miscarriage?


  1. Pelvic exam. Your health care provider might check to see if your cervix has begun to dilate.
  2. Ultrasound. During an ultrasound, your health care provider will check for a fetal heartbeat and determine if the embryo is developing normally. ...
  3. Blood tests. ...
  4. Tissue tests. ...
  5. Chromosomal tests.

Are miscarriages more common in first pregnancies?

The estimated figure is that miscarriage happens in around 1 in 4 recognised pregnancies, with 85% of those happening in the first trimester (weeks 1 to 12). A 'late' miscarriage, which is much less common, may occur between weeks 13 to 24 of pregnancy.

What happens when you miscarry at 6 weeks?

If you are less than eight weeks pregnant when the miscarriage occurs, the expelled tissue will look no different from heavy menstrual bleeding. The further along you are in pregnancy, the heavier the bleeding and more severe the cramps. ... You may or may not see tissue that looks like an embryo or fetus.

When should I take aspirin for recurrent miscarriage?

Amongst women who had a further late miscarriage, aspirin at a dose of 75 mg daily may be sufficient to maintain the pregnancies until after 14 weeks gestation, but insufficient to maintain them to the stage of viability. It is possible that higher doses of aspirin may lead to a higher livebirth rate.

How many miscarriages is normal?

For women who know they're pregnant, about 10 to 15 in 100 pregnancies (10 to 15 percent) end in miscarriage. Most miscarriages happen in the first trimester before the 12th week of pregnancy. Miscarriage in the second trimester (between 13 and 19 weeks) happens in 1 to 5 in 100 (1 to 5 percent) pregnancies.

Can you fix a miscarriage?

However, in certain situations, your doctor might suggest treatments to help reduce your risk for miscarriage. Surgery can fix some problems in the uterus (womb), like extra tissue that divides the uterus (septum), some fibroids (benign tumors), or scar tissue.

What types of autoimmune diseases cause miscarriage?

Antiphospholipid syndrome (APS) is an autoimmune disorder in which a person's immune system mistakenly makes antibodies to certain substances involved in normal blood clotting. APS is associated with repeated miscarriages and fetal deaths. Another disease that can lead to miscarriage is diabetes mellitus.

Are miscarriages genetic?

About half of all miscarriages that occur in the first trimester are caused by chromosomal abnormalities - which might be hereditary or spontaneous - in the father's sperm or the mother's egg. Chromosomes are tiny structures inside the cells of the body that carry many genes, the basic units of heredity.

Can low sperm cause miscarriage?

Men who have a higher BMI are likely to have poor quality 'fragmented' sperm, which causes an increased risk of miscarriage. - When men abstain from sex and have infrequent ejaculation, there is low semen turnover, which can lead to oxidative stress.

Can you get pregnant with unhealthy sperm?

According to a new study, though, the sperm of men whose partners' experience pregnancy losses have increased DNA damage-which islinked to bad outcomes in pregnancy. ... The host of clear medical causes, including problems with sperm, for pregnancy loss is part of the reason Williams says he avoids the word 'miscarry.'

Can low motility sperm fertilize an egg?

For the sperm to get through the cervical mucus to fertilize a woman's egg, they need to have progressive motility of at least 25 micrometers a second. Poor sperm motility or asthenozoospermia is diagnosed when less than 32 percent of the sperm are able to move efficiently.

Can males sperm cause miscarriage?

The quality of a man's semen also seems to play a role. "Poor sperm quality can be the cause [of miscarriage] in about 6% of couples," says Dr. Gavin Sacks, an obstetrician and researcher with IVF Australia. But there are probably multiple factors that, together, result in a lost pregnancy, he adds.

Can abnormal sperm cause Down syndrome?

Chromosomal Changes That Can Cause Down Syndrome. Research shows that three types of chromosomal changes can lead to Down syndrome. Complete trisomy 21. In this case, an error during the formation of the egg or the sperm results in either one having an extra chromosome.

Can sperm be tested for chromosomal abnormalities?

SAT is a diagnostic test to study the genetic etiology of male infertility. It allows us to evaluate the presence of an abnormal number of chromosomes in the sperm. In couples with severe male factor infertility, there is a higher risk of transmission of sperm chromosomal abnormalities to the offspring.

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